RESEARCH

Graduate Research Projects

Emory 10 Week Long PhD Research

Hepler Lab Rotation : Nov. 2021 - Feb. 2021

• My rotation project was to the development of high-throughput screening assays for small molecule inhibitors of the RGS14:Gαi1-GDP signaling complex.

Read Lab Rotation : Sept. 2021 - Nov. 2021

• My rotation project was to identify IMP3 candidate target transcripts maintaining the cancer stem cell state in Glioblastoma (GBM).

Undergraduate Research

Research Assistant at Grimsey Lab : Sept. 2018 - April 2021

• My project was to develop & characterize a subcellular targeted fluorescence resonance energy transfer (FRET) biosensor platform to assess the spatiotemporal activation of atypical p38 signaling.
• These FRET biosensors enabled real-time detection of p38 kinase activity at specific organelles by measuring changes in fluorescence ratios.
• Each FRET biosensor consisted of a…
  • Cyan fluorescent protein (CFP)
  • Yellow fluorescent protein (YFP)
  • Linker peptide that changes conformation upon phosphorylation by p38
  • Nuclear, plasma membrane, or diffuse/cytosolic targeting motifs